आई.सी.एम.आर.- राष्ट्रीय व्यावसायिक स्वास्थ्य संस्थान, ICMR- National Institute Of
Occupational Health अहमदाबाद - 380016 भारत. Ahmedabad - 380016 India.
व्यावसायिक स्वास्थ्य के लिए डब्ल्यूएचओ का सहयोग केंद्र. WHO Collaborating Center for
Occupational Health

Dr Gyanendra Singh

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Dr Gyanendra Singh

Biological sciences Division
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Academic Qualification

  • Ph. D. (Toxicology) –CSIR-CDRI, Lucknow & JNU, New Delhi
  • Postdoctoral Fellowship (Molecular Biology) – USA (K-State University, Manhattan, KS & LSU Health Sciences Center, New Orleans, LA)

Research Interest

  • Toxicology, Cancer biology, Infectious disease, Heavy metal toxicity, Molecular biology

Membership / Affliation

  • American College of Toxicology (Ex Full sponsored membership)
  • American Society for Virology (Ex Nominated Associate membership)
  • American Society for Microbiology (Ex Contributing membership)
  • Indian Society for the Study of Reproduction and Fertility (Life membership)

Fellowship / Awards

  • ICMR-DHR International Fellowship Award: 2019-2020. Availed fellowship at University of Pittsburgh Medical Centre (UPMC), Pittsburgh, PA, USA.
  • Received the ICMR-NIOH, Ahmedabad Scientist award for the scientific contribution - 2019.
  • Prof.GP Talwar Young Scientist Award’ at ISSRF 2017, organized by ICMR, New Delhi.
  • ICMR-IIT Kharagpur Med Tech Internship Award 2017
  • ICMR-IIT Kharagpur Med Tech Internship Award 2017-18 for 2 lakhs
  • Association of Biotechnology & Pharmacy (ABAP) - 2015 ‘Young Scientist Award’
  • Awarded international fellowship to attend ‘International Training on Environmental Toxicology’ at Chulabhorn Research Institute, Bangkok, Thailand.
  • Served as a Judge for Oral presentations at RBAT- 2017 conducted by Department of Biochemistry, University of Kerala, Kerala.
  • Served as Judge: Science Excellence- 2018 conducted by Department of Botany, Gujarat University, Ahmedabad.
  • Recognized PhD Guideship from Gujarat University, Ahmedabad and Raksha Shakti University, Ahmedabad in Toxicology subject.
  • Babu Banarasi Das University, Lucknow in accordance with CSIR-Industrial Institute of Toxicology Research, Lucknow has approved as a subject expert to evaluate and examine the PhD work in subject of Biochemistry.
  • Babu Banarasi Das University, Lucknow in accordance with CSIR-Industrial Institute of Toxicology Research, Lucknow has approved as a subject expert to evaluate and examine the PhD work in subject of Biochemistry.
  • Postdoctoral Fellowship (2007-2014), LSU Health Sciences Center/K-State University, USA Pre-Doctoral Fellowship at CSIR-Central Drug Research Institute, Luclnow.
  • Editor: Journal of Metabolomics and Systems Biology
  • Associate Editor: Universal Journal of Biotechnology & Bioinformatics
  • Lead Faculty – Toxicology; Virology – Webmedcentral, U.K.
  • Ex-Vice-President - LSU Health Sciences Center, Postdoctoral Association, New Orleans.
  • Marquis Who's Who in America 2011 Biography selected (65th Edition).
  • National Eligibility Test, CSIR-UGC (NET) - 2003.
  • National Eligibility Test, ASRB-ICAR (NET) - 2004.
  • Graduate Aptitude Test in Engineering (GATE) – 2002 with 92.39 Percentile.

Publications

  • Singh DP, Yadav SK, Patel K, Patel S, Patil GP, Bijalwan V, Singh G, Palkhade R, Kondepudi KK, Boparai RK, Bishnoi M, Das S. Short-term trivalent arsenic and hexavalent chromium exposures induce gut dysbiosis and transcriptional alteration in adipose tissue of mice. Mol Biol Rep. Nov 16 (2022)
  • Suchanti S, Awasthi S, Singh G, Yadav PK, Singh A, Mishra R. In silico prediction of COVID-19 cytokine storm in lung cancer types Biochemistry and Biophysics Reports. Dec; 32: 101350 (2022)
  • Mishra R, Haldar S, Biondi S, Bhari VK, Singh G, Bhowmick NA. TGF-β controls stromal telomere length through epigenetic modifications 3 Biotech 12, 290 (2022)
  • Tripathi S, Parmar D, Fathima S, Raval S, Singh G. Coenzyme Q10, Biochanin A and Phloretin Attenuate Cr(VI)-Induced Oxidative Stress and DNA Damage by Stimulating Nrf2/HO-1 Pathway in the Experimental Model. Biol Trace Elem Res, Aug 12 (2022).
  • Swapnil T, Shabrin F, Parmar D, Singh DP, Mishra S, Mishra R, Singh G. Therapeutic effects of CoenzymeQ10, Biochanin A and Phloretin against arsenic and chromium induced oxidative stress in mouse (Mus musculus) brain 3 Biotech,12: 116 (2022)
  • Patil GP, Yadav SK, Virmagami A, Bijalwan V, Devi K, Chauhan A; Gupta SK; Fathima S, Naorem CD Yadav S, Singh G; Mishra SD, Bishnoi M, Sarkar K, Singh DP. Occupational lead exposure is an independent modulator of hypertension and poor pulmonary functions: a case-control study. Toxicology & Industrial Health Mar;38(3):139-150 (2022)
  • Suchanti S, Stephen BJ, Awasthi S, Awasthi SK, Singh G, Singh A, Mishra R. Harnessing the role of Epigenetic Histone Modification in targeting HNSCC. Epigenomics Mar;14(5):279-293 (2022)
  • Choudhury P, Biswas S, Singh G, Pal A, Ghosh N, Ojha A, Das S, Dutta G, Chaudhury K. Immunological profiling and development of a sensing device for detection of IL-13 in COPD and asthma. Bioelectrochemistry; 143, 107971. (2022)
  • Singh G, Thaker R, Sharma A, Parmar D. Therapeutic effects of biochanin A, phloretin, and epigallocatechin-3-gallate in reducing oxidative stress in arsenic-intoxicated mice. Environ Sci Pollut Res Int. Apr; 28(16):20517-20536 (2021)
  • Shank S, Saluja S, Rawat M; Singh G, Mohammad N, Naz H, Tarique M. The causal association between occupational, environmental, and lifestyle factors and reproductive cancer risk. Current Molecular Biology Reports volume 6, pages149–160 (2020)
  • Shirish A, Mishra, SD, Kapadia V, Kumar S, Singh G. Workplace heat exposure management in Indian construction workers using cooling garment. Workplace Health & Safety Jan;67(1):18-26. (2019)
  • Sharma S, Dewan A and Singh G*. Toxico-vigilance – An inevitable prerequisite to keep a watch on toxins around you. Journal of Forensic and Legal Medicine Jan; 45:32-35. (2017)
  • Gao X, Pham TH, Feuerbacher LA, Chen K, Hays MP, Singh G, Rueter C, Guerrero RH, Hardwidge PR. Citrobacter rodentium NleB Inhibits Tumor Necrosis Factor (TNF) Receptor-Associated Factor 3 (TRAF3) Ubiquitination to Reduce Host Type I Interferon Production. Journal of Biological Chemistry. Aug 26;291(35):18232-8. (2016)
  • Singh G*, Maurya R, Kumar A and Sinha N. Role of Apoptosis in Mediating Diclofenac Induced Teratogenesis - An In Vitro Approach. Toxicology & Industrial Health 31(7) 614– 623. (2015)
  • Pham TH, Gao X, Singh G, Hardwidge PR. Escherichia coli virulence protein NleH1 interaction with the v-crk sarcoma virus CT10 oncogene-Like protein (CRKL) governs NleH1 inhibition of the ribosomal protein S3 (RPS3)/NF-kappaB pathway. Journal of Biological Chemistry. Nov 29;288 (48):34567-74. (2013)
  • Singh G*, Kumar A and Sinha N*. Studying Significance of Apoptosis in Mediating Tolbutamide Induced Teratogenesis In Vitro. Fundamental & Clinical Pharmacology Aug; 26(4): 484-94. (2012)
  • Kelly B L, Singh G, and Aiyar A. Molecular and cellular characterization of an AT - hook protein from Leishmania. PLoS One (6(6): e21412. (2011)
  • Washington A, Singh G and Aiyar A. Diametrically opposed effects of hypoxia and oxidative stress on two viral transactivators. Virology Journal May 10; 7:93. (2010)
  • Singh G* and Sinha N. Involvement of apoptosis in mediating Mitomycin C-induced teratogenesis in vitro. Toxicology Mechanisms and Methods 20(4):190-6. (2010)
  • Singh G, Aras S, Zea AH, Koochekpour S and Aiyar A. Optimal transactivation by Epstein-Barr nuclear antigen 1 requires the UR1 and ATH1 domains. Journal of Virology 83(9): 4227-4235. (2009)
  • Aras S, Singh G, Johnston K, Foster T, Aiyar A. Zinc-coordination is required for and regulates transcription activation by Epstein-Barr nuclear antigen 1. PLoS Pathogens (5(6):e1000469). (2009)
  • Aiyar A, Aras S, Washington A*, Singh G* and Luftig R B. Epstein-Barr Nuclear Antigen 1 modulates replication of oriP-plasmids by impeding replication and transcription fork migration through the family of repeats. Virology Journal Mar 5; 6:29. (2009)
  • Bhattacharjee PS, Neumann DM, Foster TP, Clement C, Singh G, Thompson HW, Kaufman HE, Hill JM. Effective treatment of ocular HSK with a human apolipoprotein E mimetic peptide in a mouse eye model. Investigative Ophthalmology and Visual Science Oct: 49(10):4263-8. (2008)
  • Toma HS, Singh G, Neumann DM, Bhattacharjee PS, Bouhnik S, Kaufman HE, Hill JM. Spontaneous Shedding of HSV-1 DNA of High and Low Phenotypic Reactivating Strains in the Rabbit Eye Model Support an Emerging Paradigm. Investigative Ophthalmology and Visual Science May: 49(13):493-493. (2008)
  • Shankar S, Singh G and Srivastava RK. Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential. Frontiers in Bioscience, 1(12):4839-54. (2007)
  • Bhadauria S, Singh G, Sinha N and Srivastava S. Isoniazid induces oxidative stress, mitochondrial dysfunction and apoptosis in Hep G2 cells. Cellular and Molecular Biology, 53: 102-14. (2007)
  • Singh G, Sinha N, Koushik JC, Mathur SK and Srivastava S. Detecting role of apoptosis in mediating cyclophosphamide induced teratogenesis in vitro. Toxicology Mechanisms and Methods, 15(6):391-7. (2005)
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